|
KMID : 1103720130680040319
|
|
Journal of the Korean Society of Radiology
2013 Volume.68 No. 4 p.319 ~ p.328
|
|
|
The Proper Scan Delay of the Hepatobiliary Phase of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging to Evaluate Small-Sized (≤ 3 cm) Hepatocellular Carcinoma in Cirrhotic Liver
|
|
Lee Ji-Hyun
Sin Sang-Su
Jeong Yong-Yeon
Heo Suk-Hee
Kim Jin-Woong
Kang Heoung-Keun
|
|
|
Abstract
|
|
|
Purpose: To assess the optimal scan delay of hepatobiliary phase of gadoxetic acid (GA)-enhanced magnetic resonance (MR) imaging for small-sized (≤ 3 cm) hepatocellular carcinomas (HCCs) in cirrhotic liver.
Materials and Methods: There were 71 HCCs included in this study, derived from 53 patients with liver cirrhosis. Hepatobiliary phase MR imaging was obtained at 10, 15 and 20 mins after GA injection. For quantitative analysis, 2 radiologists calculated signal to noise ratio (SNR), enhancement ratio (ER) of the tumor and liver parenchyma and contrast-to-noise ratio (CNR) at 10 min, 15 min, and 20 min images, respectively. For qualitative analysis, 3 radiologists independently reviewed the 3 different phase about HCC possibilities using a 5-point scale. For each observer, the diagnostic accuracy of different hepatobiliary phases was compared using the area under the alternative free-response receiver operating characteristic curve (Az). In addition, sensitivity and specificity were compared.
Results: No significant differences in SNR, ER and CNR at 10 min, 15 min, and 20 min were found. The Az values for HCC possibility were not significantly different. Sensitivity and specificity were also not significantly different.
Conclusion: Hepatobiliary phase MR imaging were obtained at 10 min, 15 min and 20 min yield comparable diagnostic information, so that the choice of scan delay can be adapted according to the clinical routine needs.
|
|
|
KEYWORD
|
|
|
Hepatocellular Carcinoma, Cirrhosis of Liver, Magnetic Resonance Imaging, Gadolinium Ethoxybenzyl, Diethylenetriamine Pentaacetic Acid
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|